Adam Garske

Company: Mammoth Biosciences

Job title: Director - Protein Engineering

Seminars:

Optimizing CasPhi for MB-111: A Multi-Component Engineering Problem 12:00 pm

Explore how MB-111, a single-dose, in vivo gene editing therapy to treat Familial Chylomicronemia Syndrome, Persistent Chylomicronemia, and Severe Hypertriglyceridemia, inactivates APOC3, resulting in durable lowering of triglycerides Understand that at the core of MB-111 is Mammoth Biosciences’ proprietary engineered CasPhi system, a hypercompact CRISPR nuclease derived from phage Investigate how engineering CasPhi required balancing…Read more

day: Day One AM