Exploring How Novel Nucleases & Appropriate Animal Models Are Key to Clinical Success
Time: 4:45 pm
day: Day Two
Details:
- Understand how engineering nucleases to improve on target efficacy and decrease off target effects was crucial to speeding up pre-clinical progression
- Evaluate how selecting mouse models and NHPs provide appropriate models to showcase efficacy and safety
- Reflect on how close collaboration between R&D and pre-clinic, as well as matching gene editing technology to appropriate indications, is essential to cut time and cost of therapeutic development
