TJ Cradick

Company: Gene Editing Frontiers

Job title: Chief Technology Officer

Seminars:

Exploring How Novel Nucleases & Appropriate Animal Models Are Key to Clinical Success 4:45 pm

Understand how engineering nucleases to improve on target efficacy and decrease off target effects was crucial to speeding up pre-clinical progression Evaluate how selecting mouse models and NHPs provide appropriate models to showcase efficacy and safety Reflect on how close collaboration between R&D and pre-clinic, as well as matching gene editing technology to appropriate indications,…Read more

day: Day Two

International Considerations: Evaluating the Impact of Obtaining Data from Outside the US 1:30 pm

Explore how obtaining initial data outside the US can expedite your process of moving into a later stage clinical trial in the US Reflect on how demonstrating safety and efficacy is crucial to de-risking scaling-up manufacturing and development, and for getting investment for other programs with similar gene editing technology Understand how trials outside the…Read more

day: Day One: Preclinical & Clinical Development

Roundtable: Reviewing Clinical Strategies to Facilitate Gene Therapies for Rare Disease & Beyond 2:00 pm

Key strategies to optimize clinical trial efficiency to accelerate time and cost-effectiveness Adjust approaches to account for population sizes to enhance therapeutic efficacy and safety Discuss emerging trends and future directions to optimize clinical strategyRead more

day: Day One: Preclinical & Clinical Development

The Future: How Baby KJ’s Personalized CRISPR Therapy Will Facilitate Better Rare Disease Targeting 9:35 am

Following the groundbreaking work to launch the world’s first personalized CRISPR therapy to treat baby KJ, a new blueprint for rare disease treatment is forming. With the baby KJ team swiftly adapting base editing technology, rapidly co-ordinating regulatory approval and redefining clinical strategies, this session offers an unmissable insight into how this pioneering approach to…Read more

day: Pre-Conference Workshop Day