Patrick van Eijk
Seminars
Thursday 30th October 2025
Platform Overview: Introduction to INDUCE-seq®, a PCR-free Method for Genome-wide Mapping of Double-strand DNA Breaks in Days, Not Months
9:30 am
Therapeutic Development:
- Data on confirming gene editing efficiency via on-target break detection Applications in iPSC and T-cell Therapies:
- Evaluation of base editor tools using INDUCE-seq®
Preclinical Safety Assessment:
- Results from the NIST genome editing program and collaboration with HESI
- Data from studies with the Innovative Genomics Institute (IGI) supporting gene editing INDs
Guide RNA Screening:
- Progress on SafeGuide AI, a predictive tool to differentiate safe versus high-risk gRNA designs
