Matthew Laurie
Senior Scientist Bristol Myers Squibb
Matthew Laurie, Senior Scientist at Bristol Myers Squibb, works in analytical development within the cell therapy division. He specializes in developing sequencing-based assays to characterize gene-edited therapies, with a focus on confirming on-target edits and detecting unintended genomic events such as translocations and vector integration. Matthew also contributes to analytical strategies for regulatory submissions and develops methods to assess the molecular purity of critical raw materials, integrating sequencing approaches with complementary techniques to ensure product quality and safety.
Seminars
Tuesday 29th September 2026
Reducing Off-Target Toxicity in CRISPR Cas9 to Demonstrate Safety & Retain Efficacy
9:00 am
- Unpacking strategies to minimize off-target toxicity in CRISPR Cas9 therapies to equip you with approaches to build a stronger safety profile for regulators
- Leveraging sequencing-based methods to assess gRNA purity, raw material quality, and genomic instability to de-risk your CRISPR therapy
- Benchmarking industry consensus on sequence purity standards for gene editing materials to help you align your analytical strategy with regulatory expectations