Jesse Owens
Chief Scientific Advisor Komo Biosciences
Seminars
Tuesday 29th September 2026
Advancing Non-Viral Gene Editing by Leveraging Hyperactive Integrases to Efficiently Deliver Targeted Large Cargo
3:45 pm
- Leveraging evolved phage integrases for non-viral, site-specific genomic integration to enhance safety and minimize off-target effects
- Engineering a super-efficient non-viral delivery system for large DNA fragments to overcome current limitations and unlock complex gene therapies
- Delivering exceptionally large therapeutic gene payloads (up to 16kb) to address complex multi-gene disorders and reduce manufacturing costs
